Abstract

ANTIBIOTICS: HISTORY AND CHALLENGES

*Sampada S. Kolhe, Dinesh S. Gujrathi, Suraj G. Malpani, Pooja R. Tange, Pooja M. Sontakke, Harsh A. Waghmare, Mayuri J. Chandrawanshi, Pravin M. Ghule and Vishweshwar M. Dharashive

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Abstract

This article provides a brief history of antibiotics from discovery to the emergence of antibiotic-resistant infections. Antimicrobial drugs selectively kill invading microorganisms without harming host cells. Resistance to antibiotics has emerged in all known classes of natural and synthetic compounds. The review explores the origin, development, and current state of antibiotic resistance, regulation, and challenges. Understanding the mechanisms of resistance and the chemical nature of antimicrobial agents is crucial in enhancing the efficiency and lifespan of antibiotics.

Keywords: Antibiotic, History, Classification, Mechanism of Action, Resistance, etc.