Abstract

RANDOMIZED CONTROL CLINICAL TRIAL OF A NOVEL COMPOUND DRUG MEDONASHAK VATI AND CHIRBILVA (HOLEPTELLIA INTREGRIFOLIA) KWATH IN THE MANAGEMENT OF MEDOROGA (OBESITY)

Acharya Balkrishan, Dr.Vijay kumar*, Pandey Awadhesh, Pathak Meenakshi S.N.

Abstract

Nowadays obesity is a great problem in both developed and developing countries, affecting children as well as adults. Prevalence of obesity is increasing day by day due to alteration in eating habits, physical inactivity, emotional disturbances, increased alcohol consumption, smoking etc. Obesity is a major risk factor for many severe diseases like hypertension, diabetes mellitus, cardiovascular disorders, joint diseases, pulmonary diseases, endocrine disorders, cancer etc. Ayurveda deals with various dimensions of life and it is related to each and every living being present in the universe. Each and every activities of individual have been aimed to achieve sukha, by the right way of living. In Ayurvedic text eight types of body traits has been described. Atisthaulya is one of them, which deserves special attention, as it has been considered as a commonest risk factor for various disorders. To evaluate the efficacy and safety aspects of a Novel Ayurvedic regimen ie Medonashak vati and Chirbilva (Holeptellia intregrifolia) kwath in medoroga, a Randomized Control Clinical Trial was conducted in 50 patients of medoroga in Department of Swasthavritta, Patanjali Bharteeya Ayurvigyan Avum Anusandhan Sansthan, Haridwar, Uttarakhand. Assessment of efficacy was done by using a self designed proforma considering the the assessment of objective parameters such as Body mass index (BMI), Total Cholesterol, Triglycerides. High density lipid (HDL), Low density lipid (LDL) and Haemoglobin (Hb%) before and after the treatment. At the end of the treatment period, symptomatic improvement was found in the patients, statistically significant (p<0.001) reduction in the parameters was noticed. No side effects were reported by the patients over the treatment period.

Keywords: Atisthaulya, Chirbilva, Medonahsak vati, Medoroga,