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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.453

ICV : 90.8

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Abstract

FORMULATION AND EVALUATION OF MICROEMULSION FOR COADMINISTRATION OF HYDROPHILIC AND HYDROPHOBIC ANTITUBERCULAR DRUGS

Triveni N. (B.Pharm)* and Deepthi Swapna P. R.

Abstract

A microemulsion has been formulated for co-administration of hydrophobic (Rifampin) and hydrophilic (Isoniazid) anti-tubercular drugs were prepared through Oil in water phase to enhance the solubility of combination drugs. The O/W microemulsion were prepared by using Oleic acid, Tween 80 and Ethanol and Evaluated for characteristic, pH, Viscometer, drug content, Zeta potential, drug release and stability study.

Keywords: Microemulsion, Hydrophilic and Lipophilic, Tween 80, Smix.

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