Abstract

COMPARATIVE STUDY OF TEA TREE OIL AND TURMERIC FORMULATIONS FOR TREATMENT OF ACNE VULGARIS – A REVIEW

*Vaibhavi C. Kambli, Kirti Chavan, Advait Pingle and Manish Bansode

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Abstract

Several bacterial species play a critical role in the development of inflammatory acne when it overgrows in pilosebaceous units. The spread of multiple drug resistance bacteria highlights the necessity for development for new antimicrobial agents. The objective of the study is to analyze different herbal phytoconstituents which show potential for the treatment of Acne Vulgaris and their placebo study effects carried on a particular Phyto constituent. Herbal Drugs selected for this study are Tea Tree Oil and Turmeric. The study delved into the mechanisms through which the selected herbal drugs exert their antiacne effects. For instance, Tea Tree Oil is known for its antimicrobial properties and Turmeric possesses anti-inflammatory and antibacterial properties.The study conducted on these herbal drugs shows a significant decrease in bacterial activity by showing Anti-acne effect. The study also incorporated a placebo-controlled design to ensure the reliability of the findings. A particular focus was placed on a placebo-controlled trial involving one of the herbal phytoconstituents, aiming to discern the true efficacy of the treatment and differentiate it from potential placebo effects. Beyond efficacy, the study considered patient tolerance and compliance with the herbal treatments. Herbal drugs are often favored for their milder nature on the skin, potentially leading to better adherence to the treatment regimen compared to more aggressive chemical-based alternatives.In addition to examining efficacy, the safety profile of the herbal drugs was thoroughly assessed. This included monitoring for adverse reactions, allergic responses, and any potential side effects to ensure that the herbal treatments maintain a high level of safety for acne patients. The findings of this study may have broader implications for future research in dermatology. It could pave the way for exploring novel herbal combinations, innovative formulations, or alternative treatment strategies for various skin conditions beyond acne.

Keywords: Pilosebaceous unit, Phytoconstituent, Acne vulgaris, anti inflammatory, anti bacterial, placebo controlled design.