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World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

UNLOCKING THE THERAPEUTIC POTENTIAL OF CHLOROGENIC ACID AND RUTIN IN CARDIOVASCULAR DISEASES: INSIGHTS FROM MOLECULAR DOCKING AND ADMET PROFILING

Dr. Maruvoor Arasi Prabu*, Ajay Samuel S., Tharani S., Chithra Devi B. S. and Ramkumar G.

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Abstract

Cardiovascular diseases (CVDs) pose a global health challenge, leading to increased mortality worldwide. This study explores the therapeutic potential of natural compounds, chlorogenic acid and rutin, using advanced molecular docking and AdMET profiling techniques. These compounds, known for their antioxidant and anti-inflammatory properties, show promise in mitigating cardiovascular risks such as hypertension, atherosclerosis, and heart failure. Molecular docking simulations reveal insights into their interactions with specific molecular targets associated with CVDs. Additionally, AdMET profiling provides crucial pharmacokinetic information. The study aims to bridge the gap between computational analysis and translational medicine, shedding light on the molecular mechanisms and evaluating the viability of chlorogenic acid and rutin as potential therapeutic agents for cardiovascular diseases, paving the way for further research and development.

Keywords: Cardiovascular diseases, Chlorogenic acid, Rutin, Molecular docking, AdMET.


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