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Abstract

CRITICALITY OF PREFILLED SYRINGE (PFS)

Natrajan Iyer, Dr. Aditya Prakash Sharma*, Rajkumar, Anmol Kumar, Namit Kumar, Arpit Sharma and Deepak Kumar

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Abstract

Administration of drug via parenteral route is advantageous for fast onset of action and 100 % bioavailability. There are number of requirements for parenteral dosage form. Prefilled syringe fulfills requirements of parenteral dosage form such as convenient means for delivery of parenteral medication, maintenance of sterility of product, dosage accuracy, increased patient compliance, improved coast efficiency, reduced product contamination and safety. Prefilled syringe contains single dose of parenteral drug with a needle fixed. This review aims to provide insight of history, manufacturing of prefilled syringe, advantages and disadvantages, directions for use, challenges and regulatory requirements related to prefilled syringes.

Keywords: #prefilledsyringe #pfs #modernparenteraladministratedevice #lowriskparenteraldevice #easyadministratedparenteraldevice #100%deliverablesafeparenteraldevice


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