WJPR Citation New

  All Since 2019
 Citation  7475  4312
 h-index  28  21
 i10-index  197  83

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
Download Article: Click Here

Search

Track Your Article

Abstract

SYNTHESIS, CHARACTERIZATION, AND ANTIMICROBIAL ACTIVITY STUDY OF 2-{3’-[(2’’’,5’’’-DIOXOIMIDAZOL-1’’’HIDINE) 4’’’-YLIDENE]METHYLENE} 1’H-INDOL-1’-YL-NARYLETHANAMIDE DERIVATIVES

Priyanka Pankhaniya*, Nikhil P. Savaniya, Neha C. Bhoraniya, Heena K. Patel, Dhruva U. Dave and Dipak M. Purohit

.

Abstract

A set of compounds labelled as 2-{3’-[(2’’’,5’’’-dioxoimidazol-1’’’Hidine) 4’’’-ylidene]methylene} 1’H-indol-1’-yl-N- arylethanamide derivatives (6a-6i) were synthesised using Knoevenagel condensation method. This involved reacting 2-(3-formyl-1H-indol-1-yl)-Narylethanamide derivatives (4a-4i) with imidazolidine-2,4-dione (5). All the synthesized compounds were characterized using advanced analytical techniques, including Mass Spectrometry, Fourier Transform Infrared (FT-IR) Spectroscopy, and Nuclear Magnetic Resonance (NMR) Spectroscopy. The compounds have been screened for antimicrobial activity against gram positive bacteria Bacillus subtilis & Staphylococcus epidermidis and gram-negative bacteria Pseudomonas aeruginosa & Proteus vulgaris. The anti-fungal activity was evaluated against Aspergillus niger. The activity of the compounds were compared with known standards such as streptomycin and nystatin.

Keywords: Indole-3-carbaldehyde, imidazolidine-2,4-dione, Knoevenagel condensation, Antimicrobial activity.


[Full Text Article]  [Download Certificate]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More