Abstract

A REVIEW ON THE MANAGEMENT OF NEPHROLITHIASIS BY ALPHA-1 RECEPTOR ANTAGONIST

A. Rajasekaran*, H. Fathima Neha, S. Sabitha, P. Bharathi, S. Murali, S. Naresh Kumar, V. S. Thiruvengadarajan

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Abstract

Nephrolithiasis is a prevalent and long-standing illness that impacts roughly 1 in 11 individuals in the United States. Renal stones are reported to have occurred in 9.4% of women and 19.1% of men by the age of 70. According to the National Health and Nutrition Examination Survey, the self-reported prevalence of kidney stones increased from 3.2% in 1976–1980 to 8.8% in 2014. This suggests that the illness burden is rising. Nephrolithiasis is treated using shockwave lithotripsy, percutaneous lithotripsy, and medical expulsive therapy utilizing corticosteroid medicines, NSAIDs, anti-inflammatory pharmaceuticals, and alpha-1 receptor antagonists. This review describes the management of nephrolithiasis by alpha-1 receptor antagonists.

Keywords: Renal calculi, management, treatment, alpha 1 receptor antagonist.