Abstract

STUDY OF ANTIHELMINTIC ACTIVITY OF CILTORIA TERNATEA FLOWER AGAINST INDIAN EARTHWORMS

Mrudula R. Gulve*, Ruchita R. Gulave and Priyanka K. Shinde

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Abstract

Clitoria ternatea or commonly known as „Butterfly pea‟ has been used traditionally in Ayurvedic medicine in which various parts of the plants are used to treat health issues such as indigestion, constipation, arthritis, skin diseases, liver and intestinal problems. The flowers of C. ternatea are used worldwide as ornamental flowers and traditionally used as a food colorant. Clitoria ternatea flower extracts were found to possess antimicrobial, antioxidant, anti-inflammatory, cytotoxic and antidiabetic activities which are beneficial to human health. Clitoria ternatea flower is a promising candidate for functional food applications owing to its wide range of pharmacotherapeutic properties as well as its safety and effectiveness. Butterfly pea (Clitoria ternatea L.) is an important perennial herbaceous plant with a range of uses as ornamental plants, fodder crops, medicine, and sources of natural food colorant and antioxidants. Development of anthelmintic resistance and high cost of conventional anthelmintic drugs led to the evaluation of medicinal plants as an alternative source of anthelmintics. The current study was aimed to evaluate the Possible anthelmintic effects of flower Extract of Clitoria ternatea Linn. Using of adult earth worm. Five concentrations (20, 10, 20, 30, 40 mg/ml) of extract were studied for the determination of Time of paralysis and death of the earth worms. Albendazole in same concentration as that of extra of flower clitoria Ternatea was Considered as standard reference and normal saline as control. The result of the present study reveals C showed paralysis and also caused death of worms especially at higher concentration Of as compared to standard reference Albendazole.

Keywords: Clitoria ternatea, anthelmintic, earthworm, paralysis, death, Albendazole.