Abstract

PREVALENCE OF H.PYLORI AMONG GASTRITIS PATIENTS IN GASTROENTEROLOGY DEPARTMENT IN A TERTIARY CARE HOSPITAL

Dr. Gopika Shaji*, Dr. Divya Hari, Dr. Jose Mathew, Lijo Joseph Thomas and Dr. Beena P.

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Abstract

Project title: Prevalence of H.pylori among gastritis patients in gastroenterology department in a tertiary care hospital. Background: In developing countries Helicobacter pylori infection is a major health ailment. The infection is related to high morbidity and mortality ranging from chronic gastritis to gastric malignancies. The prevalance of H. pylori infection greatly varies from region to region and country to country. H.pylori gastritis is the principle cause of chronic active gastritis and has major complications such as gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. Aim: The aim of the study is to determine the prevalence of H.pylori among gastritis patients in gastroenterology department in a tertiary care hospital. Materials and Methods: A retrospective cross-sectional study was conducted over a period of six months in a tertiary care hospital. A total of 100 gastritis patients were included in the study. Case records were retrospectively reviewed for demographic details, laboratory data, management and outcomes. Data analysis was conducted by using SPSS and Microsoft Excel 2019. Result: The prevalence of H.pylori was found to be 18. Gender and age has no significant effect on infection thus we conclude that infection does not depend on gender and age of the patient. While considering the association of symptoms and presence of H. pylori, there is no significant association between them. There is no significant association with the presence of H. pylori and risk factors. Out of 100 samples 54 patients were of pan gastritis and 46 patients were of antral gastritis. Conclusion: The study provides an insight into the prevalance of H.pylori.

Keywords: H.pylori- Helicobacter pylori, CagA- Cytotoxin associated gene A, ILInterleukin, ROS- Reactive oxygen species, GI- Gastrointestine.