Abstract

UPDATE ON NOVEL TARGETED DRUG DELIVERY SYSTEMS

Bhandarkar Anoosha P, Kulkarni Sughosh S, Bhandarkar Akhila P, Shetty Manjula S, Aarthy R*and Dash Devasrita 

Abstract

Novel methods of drug delivery have revolutionized the field of therapeutics. The technique of increasing the concentration of the medication in an affected/specific area of interest as compared to rest of the body by specialized way of drug delivery is termed as targeted drug delivery. This is beneficial to improvise the efficacy of medication as well as to reduce its individual dose requirement and the side effects. Targeted delivery of drugs, as the name suggests, enables the drug molecule to reach preferably to the desired tissue. Now a days in the pharmaceutical world, the research related to development of targeted drug delivery system is highly preferred and encouraged. A semiconductor nanostructure called quantum dot has made its significance in optics world due to its theoretically high quantum yield. Transdermal devices allow the drugs to be efficiently delivered across the skin barrier. Molecules irrespective of their sizes have successfully been delivered inside Folate Receptor-positive cells and tissue. For the treatment of human diseases, nasal and pulmonary routes of drug delivery are gaining increasing importance. These routes provide promising alternatives to parenteral drug delivery particularly for peptide and protein therapeutics.

Keywords: targeted drug delivery, quantum dot, folate receptor, transdermal.