Abstract

STUDY EFFECT OF HYDROGEN PEROXIDE ON TESTIS TISSUE AND THE EXTENT ABILITY OF DRUGS GLUTATHIONE AND AQUOUS EXTRACT OF NIGELLA SATIVA TO RESTRAIN

*Sara I.I.Al-Taie and Ali M.H.Al-Tamimi

Abstract

The current study was investigated effect hydrogen peroxide onnumber sperm and precentage sperm abnormalltes and in testishistological. The results of the study showed a significant decreased inthe number sperm and significant increased in precentage spermabnormalltes in group terated by hydrogen peroxide (group 2) comparewith control group at probability level P≤0.05. there are also showedresult significant decreased in spermatide, primary spermal andSpermatogina with bleeding and disintegration of intercalary tissue intestis tissue in group 2 compare with control group. showed teratedanimale by Glutathion and aquous extract of Nigella Sativa withhydrogen peroxide (group 3&4) respectively significant increased innumber sperm and significant decreased in precentage abnormalltes sperm compare withgroup2 at probability level P≤0.05. there are also showed result significant increased inspermatide, primary spermal and spermatogina with absence bleeding and suion intercalrytissue in testis tissue in group 3&4 compare with group2.

Keywords: H2O2, Glutathione, Nigella Sativa.