Abstract

A PHARMACEUTICAL CARE PRACTICE – “DRUG RELATED PROBLEMS IN IN-PATIENTS OF A TERTIARY CARE TEACHING HOSPITAL

Ramesh Bushipaka*, M. Karthik, Dinesh R, Jignesh U. Ramani, N. Phanisatyavathi and Mehul Radadiya

Abstract

Background: Drugs play a dual role in patients and they are intended to cure, prevent or diagnose signs or symptoms of a disease and on the same side its improper use cause drug related problems which leads to increased morbidity and mortality. A pharmacist in a hospital had a vital role to monitor prescriptions for drug related problems (DRP’s). A prospective study is done here, pharmaceutical care services on drug related problems in a tertiary care teaching hospital. Objectives:Toidentify the drug related problems like adverse drug reactions ADR’s, drug-drug interactions (DDI), low dose (LD), high dose (HD), To identify the patient demographics. Materials and methods: Present study is an prospective observational study conducted in a 600 bedded tertiary care hospital for a period of six months. Individual patient data with prescription content is collected every day in Peadiatric and Medicine departments in a suitable data collection form. Ethical clearance is obtained from the ethical committee before the study commence. Results: In the total data collection of 605 Prescriptions, 455 DRP’s were found. In that 7.47% (n=34) ADR’s, 71.64% (n=326) DDI, 11.86% (n=54) HD and 9.01% (n=41) LD were identified. Most of DRP’s were identified in male gender and age group of 0-20 years patients. Discussion and Conclusion:Drug related problems are one of the major problemsnow a days seen in the hospital. The study suggests that pharmacists and general practitioners (physicians) can work together to identify and resolve DRPs . Additional controlled studies are required to measure the effect of this service on health outcomes.

Keywords: DRP’s, ADR’s, Drug-Drug Interactions (DDI), High dose (HD), Low dose (LD), Pharmaceutical care services, Age group.