Abstract

THERAPEUTIC SCOPE OF TINOSPORA CORDIFOLIA IN MODERN ERA: A REVIEW

Jyoti Sharma, Ajay Kumar Ahirwar*, Madhav Varshney, Vinod Kumar

Abstract

Several medicinal plants have been claimed to have the activity of immunomodulation and Tinospora species constitute a significant class of therapeutic herbs with various pharmacological uses. Tinospora cordifolia is one, that has potential to modulate the immune system. This review article describes the prominence and information regarding the morphological, phytochemical and pharmacology aspects of T. cordifolia. It is generally acknowledged as an important herb to cure a variety of conditions, including diabetes, cancer, skin illnesses, helminthiasis, leprosy, fever, jaundice, etc. Phytochemicals have been isolated from different parts of T. cordifolia such as glycosides, phenolics, diterpenoid lactones, steroids, alkaloids, sesquiterpenoid, aliphatic compounds, essential oils, and a mixture of fatty acids. T. cordifolia possesses various notable therapeutic properties like antihyperglycemic, anti-microbial, anti-oxidant, anti-inflammatory, anticancer immunomodulatory, etc. The immunomodulatory properties of T. cordifolia along with its role as a traditional Indian herb have contributed to its use in Ayurveda and alternative medicine for treating COVID-19. The potential involvement in managing Coronavirus disease has been investigated primarily through molecular docking (in-silico research), retrospective investigations, animal experimentation, and randomized controlled trials. This review article explores the therapeutic scope of T. cordifolia, examining its uses in traditional Ayurvedic medicine as well as its relevance in modern healthcare.

Keywords: Medicinal Plants, Plant Extract, Natural Products, Immunomodulatory, Tinospora cordifolia.