Abstract

FORMULATION AND EVALUATION OF HERBAL DRUG TABLETS OF WOODFORDIA FRUTICOSA AND IN-VITRO EVALUATION OF IT`S ANTI-ULCER, ANTI-MICROBIAL AND ANTI-INFLAMMATORY ACTIVITY

E. Navya Pravala*, Uzma Tahniyath, M. Vineela, C. Anirudh, M. Sreepadha Sharma and V. Aakanksha

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Abstract

Aim: The present work aims to develop a tablet formulation of the powdered drug Woodfordia Fruticosa of varied doses and to evaluate the strength of the developed formulation. Woodfordia fruticosa is a herbal plant belonging to Lythraceae family of Sapindales. The powdered form of drug is used widely in Ayurvedic formulations as an excipient to enhance the effect of the active ingredient. Materials and Methods: The tablets are formulated using various excipients and evaluated for the strength and quality control tests such as hardness, friability, weight variation and disintegration time. The evaluated tablets were further examined for their medicinal properties. The medicinal usefulness of the drug was hypothesized depending upon the plant’s chemical composition. Results: Different doses of the tablet were prepared and the physical appearance of the drug was maintained during formulation. The hypothesized usefulness of the drug was checked through in vitro examination for various medicinal properties like Anti ulcer, Anti Microbial, Anti Inflammatory activities respectively. Suitable methods were selected for the so called In vitro examination of the drugs medicinal properties and the results obtained were further evaluated to proceed to conclusion. All the methods used for the study were approved by I.P and USP. Conclusion: The formulated tablets of Woodfordia showed positive results to all the tests and evaluation performed via in-vitro.

Keywords: Woodfordia fruticosa, Anti ulcer activity, Anti inflammatory activity, Anti microbial activity.