Abstract

HEPATOPROTECTIVE ACTIVITY OF ELYTRARIA ACAULIS IN CCL4 INDUCED HEPATO TOXIC ALBINO RATS

G. Venkat Raji Reddy*, R.Vijay Kumar, V.Rama, M. Krishna Reddy and Y. Narsimha Reddy

Abstract

Historically, the nations like the Indians, the Greeks, the Chinese, and the Egyptians have a rich account of using medicinal plants. The bulk of the population in many developing as well as developed countries still use traditional medicines, which have not been fully discovered or appreciated in modern science-based therapy. The present experiment was conducted for 07 days to evaluate the hepatoprotective activity of plant Elytraria acaulis in CCl4 (1ml/kg) treated rats. The extracts were prepared by the Elytraria acaulis whole plant extracts in ethanol and aqueous solvents through maceration technique. The 6 groups were maintained as control, CCl4 induced, CCl4+ Liver tonic, CCl4+Elytraria acaulis extracts (hydroalcoholic solvent 200mg/kg and aqueous 200mg/kg). On the 08th day blood was collected for the study of serum enzymes like SGOT (Serum Glutamate Oxaloacetic Transaminase), SGPT (Serum Glutamate Phosphate Transaminase), serum total protein, albumin and bilirubin.

Keywords: SGOT, SGPT, Alkaline Phosphate, Total protein, Albumin, Bilirubin.