Abstract

IN VITRO ANTIOXIDANT ACTIVITY OF MANGO GINGER RHIZOME

P. Jegajeevanram, N.M.I. Alhaji* and S. Velavan

Abstract

Free radicals implicated more than 100 diseases including cardiovascular diseases, cancers, neurodegenerative diseases, Alzheimer’s disease and inflammatory diseases. Natural and synthetic antioxidants are beneficial to free radical mediated diseases. Synthetic antioxidants, such as butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA), have been widely used as antioxidants in the food industry and may be responsible for liver damage and carcinogenesis but observed the side effects for long term use. For this reason, interest in the use of natural antioxidants has increased. The phenolic compounds in plants act as antioxidants due to their redox properties, allowing them to act as reducing agents, hydrogen donors, free radical quenchers and metal chelators. With this background and abundant source of unique active components harbored in plants. The chosen medicinal plant namely as Mango ginger rhizome. Hence, the free radical scavenging activity of Mango ginger rhizome were not evaluated. Therefore, the present study were to investigate the free radical scavenging activity of Mango ginger rhizome through DPPH, total antioxidant assay, superoxide, metal chelation and iron reducing power activity at different concentrations (20, 40, 60 and 80μg/ml). Throughout the studies flower extract showed marked antioxidant activity. The antioxidant activity was found to be concentration dependent and may be attributed to the presence of bioflavonoids content in the flower of Mango ginger rhizome. Overall, the Mango ginger rhizome extract is a source of natural antioxidants which might be helpful in preventing the progress of various oxidative stress mediated diseases including aging.

Keywords: Free radical, Mango ginger rhizome, Antioxidants, Oxidative stress.