Abstract

MULTIPARTICULATE DRUG DELIVERY SYSTEM AND THEIR PROCESSING TECHNIQUES

Harshal Gavali*, Divya Nair and Dhanik Patel

Abstract

Multiparticulates are discrete particles that make a multiple unit system. In pharmaceutical industry pellets can be defined as small, free flowing, spherical particulate manufactured through the cluster of fine powder or granules of drug substances and excipients using appropriate handling equipment. A present review outlines the transient account of all important manufacturing and evaluation technique of pellets. The manufacturing techniques are as spheronization and exctrusion, pelletization by solution layering, hotmelt exctrusion, cryopelletization, freeze pelletization have been deliberated

Keywords: pellets, spheronization, extrusion, cryopelletization, freeze pelletization.