Abstract

FORMULATION AND EVALUATION OF EUCALYPTUS OIL LOADED IN HERBAL GEL FOR ITS ANTIBACTERIAL ACTIVITY

Dr. Aduri Prakash Reddy*, Dr. G. Nagaraju, K. Saritha, N. Sravani, S. Sarojini and T. Chaitanya

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Abstract

Originally, the majority of antibacterial compounds was derived from plants. The term "herbal medicine" describes the use of any seed or leaf oil for therapeutic purposes. In addition to conventional dosage forms, herbal medications are also made in gel form. A gel is a semisolid substance that has a gel-like consistency and is applied topically to various body parts. Formulating and evaluating an antibacterial herbal gel using local medicinal plants was the aim of the project. For the purpose to formulate gel, the oil from the chosen plants was extracted in various ratios at random. The topical formulation was created and evaluated for a uniformity drug content, physical parameters, and Spreadability (SP). As shown by the results, the MIC values for coriander and eucalyptus herbal gel against Bacillus subtilis and Staphylococcus aureus were 50% v/v and 50% v/v, respectively. The second formulation (ECG50) displayed the highest drug content (65%), as well as the formulation's maximum stability and zone of effect. A human pathogen that can lead to infections of the skin or mucous membranes is the herpes simplex virus. Antibacterial, antimicrobial, antiviral, anti- inflammatory, and local analgesic properties are possessed by geranium, licorice, rosemary, sumac, and mellifluous plants. These herbs also have the effect of controlling the synthesis of viral proteins. The design, formulation, and assessment of the gel comprising these eucalyptus oils are the objectives of this study.

Keywords: Antibacterial, Herbal Gel, Eucalyptus oil, Formulation, Evaluation.