Abstract

REVIEW ARTICLE ON NOVEL DRUG DELIVERY SYSTEMS

Banny S.V.*, Farida Banu S., Karishma S., Hina Tousif S., Shaziya Tanzeem T., Shaguftha T. and Ganesh A.

Abstract

Based on the recently reported data, more than 70% of new drugs formulated are showing poor water solubility, which becomes the limiting factor in the absorption drug after oral admission.[1] In this respect, developed novel drug delivery system and carriers for herbal drugs should ideally accomplish some prerequisites such as proper delivering of the drug at a rate oriented by the needs of the body, over the period of treatment and it should pass the active entity of herbal drug to the site of action.[2] Many approaches have been adopted to increase drug solubility, sustainability, bioavailability and gastrointestinal permeability.[3] Nanocarrier has gained tremendous attention in the development of new pharmaceutical carrier and delivery systems. One of the strategies to thwart this problem is to encapsulate natural plant metabolites into the biodegradable and biocompatible nanoparticle.[4] Employment of innovative drug delivery systems including utilization of nanocarrier delivery to overcome the physicochemical and pharmacokinetic limitation of phytochemicals enhanced the controlled release and even efficacy of the bioactivities. This innovation shows the promising future of nanomedicine as a potential solution for impressive hindrance and handling of various chronic diseases.[5] Micro encapsulation is the process in which small droplets or particles of liquid or solid material are surrounded or coated by a continues film if polymeric material.[6]

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