Abstract

BIODEGRADABLE POLYMERS FOR TARGETED DRUG DELIVERY

Abhishek Tripathi*, Dr. T.R. Bhardwaj, Dr. Ravinesh Mishra

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Abstract

The use of biodegradable polymers has gained popularity. components for cutting-edge medication delivery systems because of their biocompatibility, controlled release properties, and environmental sustainability. These polymers—which include polylactic acid (PLA), polyglycolic acid (PGA), poly(lactic-co-glycolic acid) (PLGA), and polycaprolactone (PCL)—are perfect for pharmacological and biomedical applications since Naturally, they decompose into nontoxic by products.. Biodegradable polymer-based systems provide exact regulation of medication release Kinetics, increasing therapeutic efficacy and reducing adverse effects caused by utilising their capacity to encapsulate a range of therapeutic agents. Advanced fabrication techniques, such as nanoparticle formulation, 3D printing, and electrospinning, have further expanded their versatility, enabling the delivery of small molecules, proteins, and nucleic acids. Moreover, incorporating stimuli-responsive properties, such as pH, temperature, and enzymatic triggers, allows for targeted and on-demand drug release. Biodegradable polymer-based medication delivery systems' potential to address environmental problems pertaining to traditional synthetic materials and transform patient care through targeted, sustained, and customised medicines is highlighted in this abstract.

Keywords: Biodegradable polymers, targeted delivery, controlled release, nanocarriers, polymers nanoparticles, drug loaded polymers.