Abstract

GUT-BRAIN AXIS AND MANAS VIKARA: ROLE OF PROBIOTICS AND SATTVA ENHANCEMENT

^*Dr. Deepika Patial, Dr. Rita Singh and Dr. Babita Jamra

Abstract

The gut-brain axis (GBA) consists of bidirectional communication between the central and the enteric nervous system, linking emotional and cognitive centres of the brain with peripheral intestinal functions. Recent advances in research have described the importance of gut microbiota in influencing these interactions. GBM science based largely on preclinical studies has suggested that the gut microbiome play a role in the pathophysiology of functional GI disorders as well certain psychiatric and neurological disorders (e.g. Depression, anxiety). Mental health conditions have been linked closely to an imbalance of microbiota in the gut, leading to disruption of the microbiome (dysbiosis). Several neurotransmitters, such as GABA (gamma-aminobutyric acid), serotonin, and glutamate, are produced in the gut, which are associated with anxiety and depressive symptoms. Mental health and the gut have been linked closely, and many mental illnesses have been associated with gut dysbiosis. Probiotics are marketed to improve gut health, act as mood enhancers, and be effective in reducing stress and improvement in gut health. Alternatively, Satvavajaya Chikitsa, which emphasizes cognitive and behavioural regulation, has therapeutic potential in the treatment of various psychiatric conditions. This review aims to appraise the literature on probiotics for the prevention and treatment of mental and GI disorders. And assessing the satvavjya chikitsa in manas vikara.

Keywords: Gut-brain axis, Gut microbiota, ANS, CNS, Probiotics, Manas vikara, Satvavajya chikitsa.