Abstract

FORMULATION AND EVALUATION OF SAAMANTHI (CHRYSANTHEMUM INDICUM) BASED HERBAL OPHTHALMIC GEL FOR EYE COOLING EFFECT

Ms. E. Uma Shankari*, Mr. S. Prakash, Dr. M. Ranjith, Ms. S. Kaviya and Ms. V. Papitha

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Abstract

The growing incidence of ocular discomfort caused by environmental pollution, prolonged screen time, and digital eye strain has led to increased interest in herbal eye formulations. Chrysanthemum indicum, commonly known as Saamanthi, is a medicinal flower widely recognized for its anti-inflammatory, antioxidant, and soothing properties in traditional medicine. This study aims to formulate and evaluatea herbal ophthalmic gel incorporating Chrysanthemum indicum flower extract, intended to provide a natural cooling effect and relief from eye irritation. The gel was prepared using suitable polymers such as Carbopol 940 and Hydroxypropyl Methylcellulose (HPMC), with appropriate excipients to maintain ocular pH, isotonicity, and sterility. The formulated gel was subjected to physicochemical evaluation, including pH, viscosity, clarity, sterility, and in vitro drug release studies. Additionally, subjective evaluation of the cooling effect was performed on volunteers. The results indicated that the ophthalmic gel was physically stable, non-irritant, and provided a noticeable cooling sensation, validating its potential as a safe and effective herbal alternative for ocular therapy. Further clinical studies are recommended to establish long-term safety and efficacy.

Keywords: Chrysanthemum indicum, Saamanthi flower, Herbal ophthalmic gel, Eye cooling effect, Anti-inflammatory, Ophthalmic floccular drug delivery, Natural eye care.