Abstract

A REVIEW ON MICROEMULSION AND ITS HISTORY

*Akshay Sachin Jadhav, Dr. Amita B. Dongare and Tejas T. Ombase

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Abstract

Clear, thermodynamically stable, isotropic liquid mixes of oil, water, and surfactant—often in conjunction with a co- surfactant—are known as microemulsions. Depending on their structure, they can be categorised as bi-continuous systems, water-in-oil (w/o), or oil-inwater (o/w). They are distinguished by extremely low interfacial tension between the water and oil phases. Because of their compounds, pharmaceutical specialists are interested in microemulsions. Enhancing the microemulsion’s dissolving rate and impact on oral and other delivery methods was the aim of the study. These flexible and adaptive delivery methods enhance the solubilization of lipophilic medications and, consequently, their bioavailability while offering protection against oxidation and enzymatic hydrolysis. They can be delivered continuously and precisely via the ocular, dental, pulmonary, vaginal, and topical channels in addition to the oral and intravenous methods.

Keywords: Microemulsion, components, phase behaviour, delivery system.