Abstract

A REVIEW ON FAST DISSOLVING ORAL FILM

*Wasim Bagwan, *Kumbhar Shivam, Kotsulwar Sohan, Maniyar Hassan, Kaspate Prajakta and Pawar Jyoti

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Abstract

In comparison to other oral dose forms, this review highlights the significance of mouth dissolving films. Solid dose forms that dissolve or disintegrate in the mouth in a matter of seconds without the need for chewing or water are known as fast dissolving oral medication delivery systems. This lessens first-pass effects and promotes quick absorption in the oral cavity. Water-soluble polymers, plasticizers, active pharmaceutical ingredients (APIs), and other excipients are used in the formulation of OFDFs to guarantee stability and effectiveness. Polymers have an influence on mechanical characteristics and water absorption during the production and breakdown of films. For consistent medication delivery, API compatibility and solubility in OFDFs are crucial. Choosing the right ingredients and using a variety of strategies to improve medication delivery are the main goals of formulation development. This kind of technology provides a practical method of administering medication to the general public as well as to specific demographic groups such as children, the elderly, bedridden patients, and mentally ill people. Some businesses have developed more durable fast-dissolving medication delivery systems, including as films that are applied to the tongue's floor or top. The formulation considerations, preparation process, and quality control of the OFDFs are all described in the current review.

Keywords: Fast dissolving oral film; film forming polymers; Sustained-release; Active pharmaceutical ingredients; disintegration test time; dissolution; Packaging of OFDFs.