Abstract

A REVIEW ARTICLE ON ANALYTICAL METHODS FOR DRUG: IMEGLIMIN HYDROCHLORIDE

Bhavya Modi*, Dr. Nidhi Chauhan, Mansi Sutaria, Samiya Diwan, Khan Kaif, Kher

Abstract

Imeglimin Hydrochloride is a novel oral antidiabetic agent belonging to the glimins class, designated to target multiple pathways involved in T2DM. This article is a critical examination of the numerous analytical techniques such as the UV spectroscopy method, RP-HPLC, HPTLC, LC-MS methods as well as stability indicating methods that have been demonstrated. This study encompasses, the range of absorbance 237-420nm, solvents like dist water, MeOH, TFAA, phosphate buffers, acetone, toluene, ACN, formic acid, etc and flow rate is achieved between 0.5-1.5ml/min and retention time is range from 0.61-15 min.

Keywords: Imeglimin Hcl, UV, HPLC, HPTLC, LC-MS method, etc.