Abstract

ADVANCES IN NANOSUSPENSION TECHNOLOGY FOR IMPROVED THERAPEUTIC PERFORMANCE

Sayyad Kaufiya*, Ashte Monika, Ashte Sarika, Lokare Shubham, Jadhav Divya, Kawade Shreya and Somwanshi Shruti

.

Abstract

The study of nanotechnology examines processes that take place at the molecular level at nanoscale lengths. The current article highlights the significance of the new and exciting future of nano suspension and new age dosage forms. With regard to the particle size range of 1 to 1000 nm, nano suspension can be given orally, parenterally, or intravenously. It can also be combined with ocular inserts and mucoadhesive hydrogels for targeted drug administration. Pharmaceutical nano suspensions fall under the category of nanotechnology. They are characterised by extremely finely dispersed, biphasic, and colloidal solid drug particles in an aqueous solution. In particular, nanonization is a universal, nanospecific method of increasing the bioavailability of poorly soluble drug vehicles with sizes less than 1 um, stabilised by surfactant and polymers made using appropriate techniques for drug delivery applications. The following papers discuss the unique characteristics of nano suspensions, their preparation methods, and their benefits and drawbacks. description of patents for nano suspensions promoted the product and its use in the hopes of simplifying further study in the field of nano suspension (NS). Their distinct physicochemical characteristics and submicron particle sizes offer a flexible way to improve the delivery of drugs that aren't very soluble in lipids or water. Recants are highlighted in this review. Along with scale-down technologies and bottom-up approaches for NS creation, this article also examines a variety of in vitro and in vivo characterisation methodologies. There is discussion of a few commercial NS medicine product examples. These systems have shown great promise in the delivery of a wide range of pharmaceuticals, such as antibiotics, antiviral drugs, neuroprotective substances, anticancer agents, anti-inflammatory therapies, and poorly soluble vitamins.

Keywords: Nanotechnology, nanosuspension, solubility enhacement techniques, bioavailablity.