Abstract

CLINICOPATHOLOGICAL EVALUATION OF MENINGIOMA VARIANTS IN BASRAH CITY (2020-2024)

Zainab Ghaleb Shati* and Prof. Dr. Sawsan Salih Al Haroon

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Abstract

Introduction: Meningiomas are among the most common central nervous system (CNS) tumors. Multiple predisposing factors have been associated with increased meningioma risk. In adults, there is a distinct female predominance, with a female-to-male ratio of 3:1. It has multiple variants listed under the World Health Organization (WHO) grading system for meningiomas based on histopathological criteria into three grades. Age and sex were significant determinant in certain subtypes. Aim: The study aims to ascertain the prediction of sex and age toward a specific variant of meningioma which guide the diagnosis and prognosis prediction. Methodology: A total 216 Cases of meningioma were collected from governmental and private laboratories reports were collected; the study period was conducted from January 2020 to December 2024. Data analyzed according to age, sex, grade, and histological subtype. Results: Over a period of 5 years, meningioma cases were 216, on which we found a female predominance in this study (73.1%) with a male-to-female ratio of 1:2.7. An age-related trend was evident, with the 46–65 years group (59.7%). meningothelial meningioma was found to be the most common subtype. Conclusion: The majority of cases occurred in individuals within the fourth to sixth decades of life. A notable female predominance was observed, particularly among grade 1 meningiomas. Conversely, grade 3 (malignant) meningiomas were more frequently encountered in male patients, particularly those in the older age category.

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