Abstract

EVALUATION OF DIURETIC POTENTIAL OF LEMON JUICE AND RECONSTITUTED LEMON DRINK

Sana Sarfaraz*, Ghulam Sarwar, Wajeeha Fatima, Saima Ramzan, Raana Amjad, Ramsha Tareen and Soofia Irfan.

Abstract

Herbal Remedies have been used since ancient times because of their safety, cost efficacy, fewer adverse effects and easy availability. Herbal Remedies are again gaining their importance in field of medicine due to adverse effects and high cost of allopathic treatment. Citrus limon is also known as lemon and has been known traditionally for number of uses including its anti-oxidant properties, anxiolytic, antidepressant effect as well as diuretic potential. The study is designed to evaluate the diuretic potential of Lemon Juice (Natural) and reconstituted Lemon drink (from Powder packet) available in market so it can be incorporated as non-pharmacological treatment in hypertension and urinary diseases. Methodology: The study is carried out on albino mice weighing 18-25gm of either sex that were first familiarized with metabolic cage and then placed in it after dosing. Mice were divided into 3 groups (Standard given 1mg/kg Furosemide, Pure Lemon Juice 1ml/kg and Reconstituted Lemon Powder 100mg/kg). The dosing was done for 7 days. Result: From our study we observed mice which were given Furosemide (Standard) urinated the most, whereas pure lemon juice mice urinated moderately and mice which were given reconstituted lemon drink urinated insignificantly. Conclusion: Our study indicated pure lemon juice is mildly diuretic whereas reconstituted lemon drink result was insignificant so lemon juice can be incorporated in diet of hypertensive patient to cause diuresis naturally and lower the blood pressure. It can also be used in patient of urinary diseases to facilitate urination.

Keywords: Diuretics, Lemon Juice, Hypertension, Reconstituted.