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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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ICV : 90.8

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Abstract

REVIEW ARTICLE: FORMULATION DEVELOPMENT AND EVALUATION OF BERBERINE-LOADED BIODEGRADABLE POLYMER NANOPARTICLES

Karamveer Singh Deora* and Dr. Kamble Ravindra Keshavrao

Abstract

This review aims to provide a comprehensive analysis of the formulation development and evaluation of biodegradable polymer nanoparticles designed to encapsulate berberine and its derivatives, such as Berberine Hydroxyethyl. While direct research on the "Berberine Hydroxyethyl" derivative is limited, the principles governing the encapsulation and delivery of the parent compound, berberine, are thoroughly explored. We will delve into the properties of berberine, the selection of suitable biodegradable polymers, various nanoparticle formulation techniques, critical evaluation parameters, and the prevailing challenges and future directions that are shaping this exciting area of research.

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