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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

CASE REPORT: RIGHT RENAL DYSFUNCTION WITH URETERIC CALCULI MANAGED BY NEPHRECTOMY

*Dr. Shivam Sunil Upadhyay and Dr. Nandkishor Vitthal Borse

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Abstract

Background: Ureteric calculi are a common cause of chronic obstructive uropathy.[1] If not diagnosed and treated in time, they can lead to irreversible renal damage, loss of nephron mass[2], and systemic complications.[3] When renal function is severely compromised, surgical nephrectomy may become the definitive option. Case Presentation: We report a case of a 59-year-old female who presented with a 15-day history of bilateral loin to groin pain, burning micturition, and increased urinary frequency. Imaging revealed a small, atrophic right kidney with two mid-ureteric calculi and mild fullness of the pelvicalyceal system. Renal functional scan demonstrated only 5.26% contribution from the right kidney (GFR: 2.35 mL/min). The left kidney showed compensatory hypertrophy with preserved function. The patient underwent a right nephrectomy with partial ureterectomy under general anaesthesia. The procedure was uneventful. Histopathology confirmed chronic pyelonephritis with severe interstitial fibrosis and tubular atrophy. Conclusion: This case highlights the importance of early detection and timely intervention in chronic obstructive uropathy. Nephrectomy is the definitive and safe treatment for non-functioning kidneys with irreversible damage, aimed at symptom relief and complication prevention.

Keywords: Obstructive uropathy, Ureteric calculi, Nephrectomy.


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