Abstract

PHYSICOCHEMICAL STANDARDIZATION OF THE TRADITIONAL SIDDHA POLYHERBAL FORMULALTION MAANTHA KULIGAI

Dr. M. Soundarya*, Dr. C. Shanmugapriya, MD(S), Dr. A. Satheesh Kumar, MD(S)

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Abstract

Introduction: Siddha Medicine, a valuable part of India’s rich traditional heritage, represents an ancient system that offers a holistic and compassionate approach to health. This system primarily uses natural substances such as plants, minerals, and metals to treat a variety of diseases. Although many Siddha medicines have demonstrated therapeutic benefits, most lack proper standardization. Standardizing Siddha polyherbal formulations is essential to establish detailed monographs, ensuring the genuineness, purity, and safety of these preparations for patient use. Maantha Kuligai (MK) is a classical Siddha polyherbal formulation has been used to manage various neurological condition including Autism spectrum Disorder. (ASD). Standardizing such formulations through physicochemical evaluation is important for assuring consistent quality and efficacy. Aim and Objective: To establish reliable quality control measures for Maantha Kuligai, a Siddha polyherbal formulation, by conducting comprehensive physicochemical analysis to ensure its authenticity, effectiveness, and safety. Materials and Methods: Maantha Kuligai was prepared following traditional Siddha methods as documented in the Siddha text, Bala Vaithiya Thirattu.Its physicochemical properties, such as moisture level, ash content, extractive values, and pH, were evaluated using established standard procedures to verify its quality and uniformity. Results: The physicochemical evaluation of Maantha Kuligai revealed a moisture content of 3.23 ± 0.32%, total ash value of 1.73 ± 0.20%, and no detectable acid-insoluble ash. The water-soluble extractive was found to be 10.03 ± 0.55%, while the alcohol-soluble extractive measured 8.33 ± 0.20%. The pH of the formulation was recorded as 6.44, indicating a slightly acidic nature. Conclusion: The physicochemical evaluation of Maantha Kuligai confirms its compliance with key quality standards, supporting its traditional use in Siddha medicine. These findings serve as a foundation for further standardization and future pharmacological or clinical investigations.

Keywords: Maantha kuligai, Physiochemical Standardization, Bala Vaithiya Thirattu.