Abstract

INTEGRATING TRADITIONAL MEDICINE WITH MODERN FORMULATION: A POLYHERBAL APPROACH TO ANTICOAGULATION BY ALLUM SATIVUM, ZINGIBER OFFICINALE, SYZYGIUM AROMATICUM EXTRACT

*Mayur Premanand Chaudhari, Khushi Avinash Patil, Dipali Digambar Chaudhari, Dhiraj Ashok Mate, Vaishnavi Kishor Shinde and Mohammad Awais

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Abstract

Blood clot formation and abnormal platelet activity are major factors contributing to cardiovascular diseases, which continue to rank among the top global health concerns. Plant-based therapies have gained increasing attention as safer and more versatile options compared to conventional anticoagulant drugs. In this research, a polyherbal anticoagulant syrup was developed using a carefully balanced combination of Garlic (Allium sativum), Ginger (Zingiber officinale), and Clove (Syzygium aromaticum), supported by stabilizing agents including EDTA, ascorbic acid, xanthan gum, and HPMC. The selected botanicals were chosen for their well-documented ability to reduce platelet aggregation, support healthy blood circulation, and counteract oxidative stress–related clot formation. The prepared formulation was tested for physicochemical attributes such as pH, viscosity, sensory characteristics, and microbial safety. Results showed that the syrup remained stable in appearance and texture, was free from microbial contamination, and demonstrated strong potential as a natural alternative for anticoagulant therapy.

Keywords: The prepared formulation was tested for physicochemical attributes such as pH, viscosity, sensory characteristics, and microbial safety.