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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

METHOD DEVELOPMENT AND METHOD VALIDATION OF CEFTAZIDIME AND AVIBACTAM BY RP-HPLC

*Prudhvi Sai Krishna Akula

Abstract

Using a Waters PDA-detected HPLC mode and a quick, sensitive, and precise RP-HPLC approach, Avibactam and Ceftazidime have been identified and quantified. An Inertsil-ODS C18 (250 x 4.6 mm, 5) column was used to separate Avibactam and Ceftazidime at a volumetric rate of 1.0 ml/min. The filtered mobile phase of the process was combined with degassed Methanol and Acetonitrile (70:30), and the wavelength of detection was 275 nm.

Keywords: Ceftazidime, Avibactam, RP-HPLC.

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