Abstract

THE PHYTOCHEMICAL PROFILE AND ANTI-MICROBIAL EFFICACY OF CITRULLUS COLOCYNTHIS PULP EXTRACT

Ms. Pratheeksha B. R., Dr. Urmila G. H.*, Ms. Bhavana N. M., Dr. Rama R. Nargund*, Dr. Shachindra L. Nargund

Abstract

This article provides a comprehensive overview of the antibacterial properties of Citrullus colocynthis pulp extract, a medicinal herb traditionally used for numerous health conditions, was evaluated for antibacterial properties using the Cup plate Agar diffusion method. The extract exhibited broadspectrum antimicrobial activity against bacterial strains and there was no observed relationship between the microorganisms resistance to antibiotics and their susceptibility of the plant extract. Phytochemical analysis of the bioactive extracts revealed the presence of alkaloids, glycosides, flavonoids, Carbohydrates. It possesses many pharmacological properties such as anti-oxidant, anti-microbial, diuretic, hypolipidemic, anti-cancerous activity. When compared to standard antibiotics-amoxicillin, the extract showed notable antimicrobial effects. These findings indicate the potential use of Citrullus colocynthis in managing infections caused by the tested pathogens.

Keywords: Citrullus colocynthis, Antibacterial activity, Phytochemical analysis, Cup plate Agar diffusion method.