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Abstract

ROLE OF AYURGENOMICS IN PERSONALIZED MEDICINE

Dr. Jitendra Patel*, Dr. Mayank Singh, Dr. Pravanjan Acharya

Abstract

Ayurveda is an ancient Indian system of medicine that uses a systems approach to understand and control health and disease. It has some interesting connections with modern personalised genomic medicine approaches to health and disease management. It is founded on the trisutra, which consists of three parts of causes, characteristics, and therapies that are linked by a single organising principle known as tridosha. Tridosha is made up of three physiological entities: vata (kinetic), pitta (metabolic), and kapha (potential) that are found throughout the body, function together, respond to the environment, and maintain equilibrium. Each person is born with a unique proportion of tridosha that is determined not just by genetics but also by the environment during foetal development. To forecast the phenotypic repercussions of aberrations, modern medicine focuses on genetic, cellular, physiological, and environmental networks. Ayurgenomics is an integrated method that combines Ayurvedic Prakriti notions with contemporary genetics research. It links the three doshas of vata, pitta, and kapha to the expression of genetic and physiological individuality. Ayurvedic medicine views each person as unique, and sickness as the result of a complex interaction of internal and external causes. The Ayurgenomics study thus presents a fresh molecular framework for merging genomics investigations with Ayurvedic concepts of inter-individual variability, thereby speeding up the finding of markers for predictive, preventative, and personalised therapy. Using the capabilities of genomics and molecular phenotyping, the Ayurgenomics technique enables for systematic research of Trisutra Ayurveda. Ayurgenomics may open the way to achieving preventive and personalised medicine aims more quickly.

Keywords: Ayurgenomics is an integrated method that combines Ayurvedic Prakriti notions with contemporary genetics research.


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