Abstract

REVIEW ARTICLE ABOUT FUTURE ASPECT OF TOPICAL DRUG DELIVERY SYSTEM

Mrs. D. Punitha*, Dr. J. Jaslin Edward, Mrs. T. Jaghatha, Akash P., Bershiya R., Jeya Jothi C. S., Nisha D. S., Vibisha V.

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Abstract

Topical drugs have achieved widespread adoption as cosmetic, topical and transdermal delivery mechanisms. These systems constitute a significant achievement resulting from advances in dermatological science, technological innovation, and specialized knowledge accumulated through experimental approaches, clinical observations, and research- based investigations spanning back to the earliest documented human practices. This examination commences and with the most ancient topical treatments and follows the progression of topical administration to contemporary transdermal patches, detailing the preliminary experiments, apparatus, and pharmaceutical delivery mechanisms that form the foundation of modern transdermal patches and their therapeutic compounds. Subsequently, the discussion addresses the development of various patch configurations and their constraints, alongside the criteria for therapeutic agents suitable for trans dermal administration. The characteristics of and challenges related to commercially available products, including inconsistency, safety concerns, and regulatory considerations, are subsequently outlined. The examination concludes by exploring future opportunities for transdermal patches and pharmaceutical delivery mechanisms, including the integration of therapeutic delivery systems with patches, minimally invasive microneedle applications, and dermal formulations, encompassing measured- dose delivery systems.

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