Abstract

ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF LEAVES EXTRACT OF SOYMIDA FEBRIFUGA A.JUSS.

Shubhangi Sharad Bhide, Suvarna Prabhakar Gajare, Kirti Sahu, ACP, Wardha.

Abstract

Rohan, soymida febrifuga plant belonging to family meliaceae.The bark of this plant has been proven to have many pharmacological activities. In this experiment the antimicrobial activities of the plant leaves were studied on different bacteria and fungus using different techniques like well diffusion method and minimum inhibitory concentration. In the well diffusion method petroleum ether,chloroform,methanol, water and total aqeous were prepared and tested against some gram positive strains(B.subtillis,S.aureus) and gram negative strains( E.coli, P.vulgaris, P.aeurginosa) and were compared with standard(tetracycline).The water(zone of inhibition 23.33) and total aqeous (17.6) gave very significant result to compare with the standard (24) for S.aureus. By minimum inhibitory concentration the result on different strains were studied, like A.niger,A.flavones,P.aeurginosa and C. albicans. The methanol and water extract gave thebmost significant result the MIC(mg/ml) for water extract against P.aeurginosa and C.albicans were found to be 1.25 mg/ml.

Keywords: soymida febrifuga, antibacterial, antifungal, Minimum inhibitory concentration.soymida febrifuga, antibacterial, antifungal, Minimum inhibitory concentration.