Abstract

REVIEW ON: THIN FLIM LAMOTRIGINE TREATMENT FOR CHILDHOOD EPILISY

Miss. Radha Manohar Bakhade*, Miss. Mayuri Anil Kalaskar, Mr. Mayur Udhay

Abstract

Epilepsy in childhood poses a significant challenge to healthcare providers and caregivers alike. necessitating effective and tolerable treatment options. Lamotrigine, an antiepileptic drug, has gained attention for its potential efficacy in managing childhood epilepsy. This review systematically examines the existing literature on thin film formulations of lamotrigine, specifically focusing on their use in treating Pediatric epilepsy. Inclusion criteria encompassed clinical trials, observational studies, and case series that investigated the use of thin film lamotrigine in Pediatric patients diagnosed with epilepsy. The synthesis of data includes an in-depth analysis of seizure outcomes, adverse events, pharmacokinetic profiles, and patient adherence to thin film lamotrigine therapy. Additionally, this review explores the practical aspects of thin film formulations, such as ease of administration, convenience, and overall patient and caregiver satisfaction. Lamotrigine is considered a broad-spectrum antiepileptic drug. It is an antiepileptic drug (AED) that is primarily used for the treatment of epilepsy and bipolar disorder. It works by stabilizing electrical activity in the brain and affecting the way nerves send messages to the brain.

Keywords: Lamotrigine. Seizure. Anti-epileptics, Childhood epilepsy.