Abstract

REVIEW ON “UNRAVELLING THE TRADITIONAL WISDOM OF BRYOPHYLLUM PINNATUM: MODERN INSIGHTS AND THERAPEUTIC IMPLICATIONS

Harshal S. Singh, *Vishal S. Madankar, Mr. Anil B. Panchal

Abstract

Bryophyllum pinnatum, A member of the Crassulaceae family, is a widely distributed medicinal plant that has long been utilized in tropical countries for Ayurvedic, homeopathic, and folk medicine purposes. Often referred to as the "miracle plant," "air plant," or "life plant," it has unusually succulent leaves that may reproduce vegetatively by producing plantlets on the leaves. The plant's rich phytochemical composition and varied pharmacological profile have drawn a lot of scientific interest. Anti-inflammatory, analgesic, antibacterial, antioxidant, antidiabetic, antiurolithiatic, wound-healing, hepatoprotective, immunomodulatory, and anticancer properties have all been shown in B. pinnatum's leaves, roots, and stems. Its secondary metabolites, including as flavonoids, phenolic compounds, glycosides, tannins, triterpenoids, alkaloids, and steroids, are responsible for these biological characteristics. B. pinnatum is used in traditional medical systems to treat conditions like fever, asthma, hypertension, skin infections, kidney stones, ulcers, and gastrointestinal issues. Its potential for neuroprotection and reproductive health has also been highlighted by recent studies. Many ethnomedicinal claims have been confirmed by preclinical research, but there are still few thorough clinical assessments available. To guarantee safety and therapeutic efficacy, extract standardization, toxicity profiling, dosage adjustment, and thorough mechanistic research are necessary. Furthermore, potential to improve the bioavailability and therapeutic uses of its bioactive ingredients are presented by developments in formulation science and biotechnology. This review covers Bryophyllum pinnatum's botany, phytochemistry, and pharmacological properties to help with future scientific research and drug development. Strengthening evidence-based research will facilitate its incorporation into modern healthcare as a promising natural medicine with extensive therapeutic potential.

Keywords: Bryophyllum Pinnatum, Miracle Plant, Traditional medicine, Phytochemistry Anti-inflammatory, Analgesic, Antibacterial, Antiurolithiatic.