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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.

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Abstract

EFFECT OF COLEUS AROMATICUS LINN., ON CCL4 INDUCED HEPATOTOXICITY IN SWISS ALBINO RATS

Dr. Jayachitra J.* and Dr. Chitra M.

Abstract

The present study has been carried out to evaluate the effect of coleus aromaticus leaves on CCl4 induced hepatotoxicity in swiss albino rats. Elevation of SGOT, SGPT, LDH, GGT and decline in NADHdehydrogenase, Glucose-6-phosphatase, Na+/K+ dependent ATPase, Total ATPase and ca2+ ATPase was noted in CCl4 administred rats. Total reversal of all the above said parameters was noted in both ethanolic extract treated and Silymarin treated rats. The efficacy of the plant drug has been found to be more than the standard drug Silymarin.

Keywords: Biochemical analysis, Coleus aromaticus.

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