Abstract

SOLID LIPID NANOPARTICLES: RECENT ADVANCES IN NOVEL DRUG CARRIER SYSTEMS

Ram Chandra Jat*, Kanika Arora, Nidhi Anuragi, Rakhi Kaushal, Dr. Vinay Jain

Abstract

Solid lipid nanoparticles (SLN) have emerged as a next-generation drug delivery system with potential applications in pharmaceutical field, cosmetics, research, clinical medicine and other allied sciences. The present review focuses on the utility of SLN in terms of their advantages, production methodology, characterization and applications. Solid lipid Nanoparticles were developed in early 1990s as an alternative to other traditional colloidal carriers like liposome’s, polymeric Nanoparticles and emulsions as they have advantages like controlled drug release and targeted drug delivery with increased stability. SLNs are rapidly developing nanotechnology with several applications in drug delivery system, clinical medicine and other science. The ability of SLNs to incorporate drug into nanocarrier that offer new type in drug delivery system. Therefore SLNs is reaching the goal of controlled and site specific drug delivery system.

Keywords: Solid lipid Nanoparticle drug delivery.