Abstract

ANTIMICROBIAL AND RADICAL SCAVENGING ACTIVITY OF GYMNOSPORIA MONTANA (ROTH.) BENTH

Anjana N. Raikar, Nagashree P.S, Sinchana C.V, Swathi B.B, Prashith Kekuda T.R*, Raghavendra H.L

Abstract

Gymnosporia montana (Roth.) Benth. belonging to the family Celastraceae grows in arid and dry areas of India and other countries. In the present study, we determined antimicrobial and radical scavenging efficacy of leaf, flower and fruit extract of G. montana. Antibacterial and antifungal activity of extracts was determined by Agar well diffusion and Poisoned food technique respectively. Radical scavenging efficacy of extracts was evaluated by DPPH free radical scavenging assay. Overall, fruit extract displayed marked antimicrobial activity when compared to leaf and flower extracts. Leaf extract scavenged DPPH radicals more effectively than flower and fruit extracts. Fruit extract displayed least radical scavenging potential. In suitable form, the plant can be used to control/treat microbial infections and oxidative stress.

Keywords: Gymnosporia montana, Agar well diffusion, Poisoned food technique, DPPH.