Abstract

INVESTIGATION ON PHAGOCYTOSIS INDEX & SERUM (IGE, IGG, IGM) IN PATIENTS OF ASTHMA IN THI-QAR PROVINCE

Ali Naeem. Salman* and Hind Hussein Saleh

Abstract

The current study was conducted at the Al-Hussein Teaching Hospital in Thi- Qar province, during the period from October 2014 to May 2015.The study aimed to evaluate immune status of asthmatic patients by measuring the levels of immunoglobulin ( IgE ) by enzyme-linked immunosorbent assay (ELISA) and immunoglobulin(IgG,IgM) by single radial immune diffusion (SRID). the study included test phagocytic cells on phagocytosis (coefficient of phagocytosis). The study included a total of 100 patients with asthma (68 female) and (32 males) and there aged between 17-62 years. The results of the statistical analysis showed high significant increase (P ≤ 0.001) in serum IgE,, IgG of patients with asthma compared with healthy control group . and no significant difference in serum IgM of patients with asthma compared with healthy control group. Decrease coefficient phagocytosis was significantly (P ≤ 0.001) in all patients with asthma compared with healthy control group.

Keywords: Asthma, IgE, IgG, IgM, Phagocytosis, THI, QAR.