Abstract

EXPLORING THE WOUND HEALING EFFICACY OF SACCHARUM OFFICINARUM STEMS THROUGH COMPUTATIONAL DOCKING ANALYSIS

Dr. R. Mariyammal*, Monisha S.

Abstract

The biological process of wound healing is intricate and includes collagen synthesis, tissue restoration, and microbial infection management. This work uses computational molecular docking and phytochemical analysis to assess the wound-healing potential of Saccharum officinarum (sugarcane) stem extract. Bioactive substances like flavonoids and phenolics, which may support tissue regeneration and antibacterial activity, are present in the extract. Strong binding interactions between plant chemicals and protein targets linked to wound healing were demonstrated by docking experiments, indicating possible therapeutic utility. Overall, the study suggests that sugarcane stems could be used to create plantbased compositions for wound healing.

Keywords: Wound healing, Molecular docking, Phytochemicals, Antimicrobial activity, Plant-based therapeutics, Stem extract.