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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

SANGYASTHAPAK GANA DHOOPAN VARTI: A COMPREHENSIVE STUDY ON ITS NEURO-MODULATORY ROLE IN THE MANAGEMENT OF AUTISM SPECTRUM DISORDER (ASD)

Dr. Aishwarya G. Futane*, Dr. Vijay S. Suryawanshi, Dr. Vishal B. Ratnaparkhi

Abstract

Background: Autism Spectrum Disorder (ASD) involves complex neuro-psychological deficits where oral drug delivery is often hindered by sensory aversions. Dhoopana Karma (medicated fumigation) using Sangyasthapak Gana offers a non-invasive, nasal-to-brain delivery system. Objective: To evaluate the therapeutic potential, phytochemical basis, and pharmaceutical preparation of Sangyasthapak Gana Dhoopa Varti in managing pediatric autism. Methods: A review of classical texts (Charaka Samhita, Kashyapa Samhita) and modern databases was conducted. A standardized method for preparing Dhoopa Varti (medicated wicks) was developed. Results: Phytochemicals like Bacosides, Asarones, and Jatamansone bypass the blood-brain barrier via the olfactory pathway, modulating GABA-ergic and cholinergic systems to reduce hyperactivity and enhance cognition. Conclusion: Sangyasthapak Dhoopana is a safe, scientifically sound adjunct therapy for neuropsychological stabilization in ASD.

Keywords: Kaumarabhritya, Autism, Sangyasthapak Gana, Dhoopana, Varti, Neuro-psychology.


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