Abstract

FORMULATION AND EVALUATION OF ANTIDIABETIC SYRUP CONTAINING TINOSPORA CORDIFOLIA

Miss. Dakshata Sunil Bhosale*, Miss. Samidha N. Sonkamble, Miss. Asmana Shaik, Miss. Shraddha V. Kamble, Miss. Srushti Bhoir, Miss. Tejaswini Asawe, Dr. Rajnikanth Kakade

Abstract

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia and associated complications such as neuropathy, nephropathy, and cardiovascular diseases.[10] The limitations of synthetic antidiabetic drugs, including adverse effects and long-term toxicity, have led to increased interest in herbal alternatives.[17] Tinospora cordifolia (Giloy), a widely used medicinal plant in Ayurveda, has demonstrated significant antidiabetic potential due to its rich phytochemical profile.[12] This review provides a comprehensive overview of the phytochemistry, pharmacological activities, mechanisms of action, and formulation strategies of Tinospora cordifolia-based antidiabetic syrup.[10] The syrup dosage form offers improved patient compliance, stability, and bioavailability.[12] Additionally, evaluation parameters and clinical evidence supporting its efficacy are discussed. The review concludes that Tinospora cordifolia syrup represents a promising and safe herbal formulation for diabetes management, although further standardization and clinical validation are required.[17]

Keywords: Tinospora cordifolia, Antidiabetic syrup, Herbal formulation, Giloy, Diabetes mellitus, Phytochemistry.