Abstract

FORMULATION AND EVALUATION OF ANTIOXIDANT SYRUP FROM ACHYRANTHES ASPERA

*Sudarshan Anand Shelke, Rachana Kamble, Akashay Fulsundar, Pooja Changdev Gawande

Abstract

The present study focuses on the formulation and evaluation of an antioxidant herbal syrup prepared from Achyranthes aspera (Aghada), a plant widely recognized for its therapeutic potential in traditional medicine. The aerial parts of the plant were subjected to extraction using a suitable solvent system to obtain a concentrated extract rich in bioactive constituents. Preliminary phytochemical screening of the extract revealed the presence of flavonoids, phenolic compounds, alkaloids, and saponins, which are known to exhibit significant antioxidant activity. The antioxidant syrup was formulated using the prepared extract along with suitable excipients such as sucrose, preservatives, and buffering agents to ensure stability, palatability, and safety. The formulated syrup was evaluated for various physicochemical parameters including pH, viscosity, specific gravity, and organoleptic properties. In addition, antioxidant activity was assessed using standard in vitro methods, demonstrating promising free radical scavenging potential attributed to the phenolic and flavonoid content of the extract. The formulation showed acceptable stability and compliance with standard quality control parameters for herbal syrups. The study concludes that Aghada-based antioxidant syrup can serve as a potential natural therapeutic agent, offering an effective and safer alternative to synthetic antioxidants. Further studies are recommended to explore its clinical efficacy and long-term stability.

Keywords: Antioxidant activity, Free radical scavenging activity, DPPH assay, Polyherbal preparation, Medicinal plants, Syrup formulation.