Abstract

DESIGN OF PHYTO-BASED NANOEMULGEL FOR TARGETED ACNE THERAPY

Miss. Akanksha Wasudeorao Bhute*, Mr. Mayur Udayrao Dongare, Miss. Lochani Suresh Gajbhiye, Prof. Vishnudas Lokhande, Dr. Rahul Bijwar

Abstract

Acne Vulgaris Is A Common Skin Condition That Mainly Affects Teenagers And Young Adults And Is Linked With Inflammation, Bacterial Growth, And Excessive Sebum Production. Although Conventional Treatments Are Effective, They Often Lead To Side Effects Such As Skin Irritation, Dryness, And The Development Of Antibiotic Resistance. The Present Study Focuses On The Formulation And Evaluation Of A Polyherbal Nanogel Containing Natural Ingredients With Anti-Inflammatory, Antimicrobial, And Antioxidant Activities. The Selected Herbal Components Include Turmeric (Curcuma Longa), Neem (Azadirachta Indica). These Ingredients Were Incorporated Into A Carbapol-Based Nanogel System Using Water As A Solvent, While Triethanol -Amine Was Used To Adjust The Ph. High-Speed Homogenization Was Employed To Achieve Uniform Mixing And Nanoscale Dispersion Of The Active Compounds. The Prepared Nanogel Was Evaluated For Various Physicochemical Properties Such As Ph, Spreadability, Viscosity, Washability, Consistency, Greasiness, And Appearance. The Formulation Showed A Ph Of 5.7 And Exhibited Good Stability, Smooth Texture, Non-Greasy Nature, And Acceptable User-Friendly Characteristics.

Keywords: Acne Vulgaris, Azadirachta Indica, Curcuma Longa, Antimicrobial, Anti- Inflammatory, Antioxidant, Anti-Acne Gel, Herbal Formulation.