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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

A CRITICAL REVIEW ON ANKYLOSING SPONDYLITIS IN THE LIGHT OF TRIKA-KATI-PRISHTA GRAHA – LITERARY RESEARCH BASED CONCEPTUAL STUDY

Dr. Chandana K.*, Dr. A. S. Prashanth, Dr. MD. Yaseen Hullur

Abstract

Ankylosing Spondylitis (AS) is a chronic inflammatory autoimmune disorder predominantly affecting the axial skeleton, characterized by progressive pain, stiffness, and structural deformity. Despite advancements in pharmacotherapy, current management remains largely symptomatic with significant long-term limitations. Ayurveda does not describe AS as a distinct clinical entity; however, its symptomatology closely resembles Trika-Kati-Prishta Graha, a subtype of Vata Vyadhi associated with Ama. This review critically evaluates the pathogenesis, clinical features, and progression of AS through Ayurvedic principles, emphasizing the roles of Mandagni, Ama formation, and Tridoshic imbalance. Classical references are systematically analyzed and correlated with contemporary biomedical understanding. The study highlights that AS can be interpreted as a Sama Vata disorder involving Asthi and Majja Dhatu. This integrative approach provides a deeper understanding of disease mechanisms and suggests potential for holistic and root-cause-based management strategies in Ayurveda.

Keywords: sankylosing Spondylitis, Trika graha, Kati Graha, Prishta Graha, Samavataja Vyadhi, Ayurveda.


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